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mec Foster Wheeler (now Wood)   The table 1 indicates the main project milestones.
                                             and Bracco have a long and conso-  There were two fundamental aspects instrumental
                                             lidated tradition in working together   to the success of the project:
                                             in project execution, especially focu-  •   to execute the structural design of the building
                                             sed on the Italian territory. The Spin   during the basic design, to allow early con-
                                  AProject at Torviscosa (Udine) and the       struction starts and to identify the civil contrac-
                                  Bracco Project at Ceriano Laghetto (Monza Brian-  tor as early as possible, considering the legal
                                  za) have been their two main undertakings, prior   requirements and regulatory constraints for
                                  to the implementation of the “Hermes Project” lo-  construction in Germany;
                                  cated in Singen (Baden Württemberg, Germany) in   •   to develop the detailed design of the plant
                                  the period 2015-2017.                        installation,  such us  piping,  HVAC (Heating
                                  Bracco is an international Group active in the   Ventilation Air Conditioning), electrical & instru-
                                  healthcare sector and leader in diagnostic imaging.   mentation with the selected work contractors
                                  It  has  around  3,450 employees  and annual  total   considering the proper coordination and inte-
                                  consolidated revenues of around 1.3 billion euro, of   gration of the main equipment purchased di-
                                  which 87% from international sales.          rectly by us.
                                  BIPSO (Bracco Imaging Pharmaceutical Sterile
                                  Operations) is specialised in the production of ster-  This article describes some key elements and pe-
                                  ile pharmaceutical products. It is the most impor-  culiarities of the project:
                                  tant sterile manufacturing site of the Bracco Group   •   site plan and integration with the existing fa-
                                  and manufactures and packs imaging agents for   cilities;
                                  the sales organisation of Bracco Imaging and ster-  •   permitting and certifications;
                                  ile drugs as contract manufacturer for other com-  •   construction and commissioning & qualifica-
                                  panies in the pharmaceutical industry.       tion (C&Q) highlights.

                                  Project description                      Master Plan and integration
                                  After the Feasibility Study phase, during the exe-  with the existing facilities
                                  cution of the Basic Design, Amec Foster Whee-
                                  ler (now Wood) and Bracco agreed on a flexible   Master planning is a complex exercise while en-
                                  project execution for the subsequent phases of the   compassing an existing site modification. Flexibility
                                  project, with specific attention on cost and sche-  and foresight were the two design drivers of Brac-
                                  dule.                                    co and Amec Foster Wheeler (now Wood).
                                  The scope of services included:          Site Master Plan was entirely studied, in conside-
                                  •   procurement of main equipment and subcon-  ration of the low term and the medium / long term
                                     tracting works;                       investment plans. Four main block functions were
                                  •   preparation of documentation for building per-  identified as part of the Master Plan:
                                     mit application;                      •   quality control laboratories;
                                  •   civil construction drawings according to local   •   office expansion;
                                     rules (Rotpunkt), executed with the Architect   •   warehouse and logistic;
                                     Studio Mussgnug-Wirth-Kramer;         •   site infrastructure upgrade.
                                  •   project control and cost control services;
                                  •   construction management and supervision up   Quality Control Laboratory Building W40 (in light
                                     to mechanical completion;             green, centre of the  figure 1) was conveniently
                                  •   management of commissioning.         placed near the production facility, connected by



                                 Table 1 - The main project milestones of the “Hermes Project”

                                         Milestone                                 Date
                                         Basic design start                        31.01.2015
                                         Detailed design start                     19.08.2015
                                         Kick-off meeting                          03.09.2015
                                         Site opening                              15.09.2015
                                         Mechanical completion                     23.12.2016
                                         Commissioning & qualification completion  31.03.2017




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